2023
Akowuah E, Maier R, Hancock H, Kharatikoopaei E, Vale L, Fernandez-Garcia C, Ogundimu E, Wagnild J, Mathias A, Walmsley Z, Howe N, Kasim A, Graham R, Murphy G, Zacharias J, Minithoracotomy vs Conventional Sternotomy for Mitral Valve Repair; A Randomized Clinical Trial, JAMA, 2023;329(22):1957-1966 doi:10.1001/jama.2023.7800
Harrison S, Loughran K, Trevis J, Witharana P, Maier R, Hancock H, Bardgett M, Mathias A, Akowuah E, Experiences of patients enrolled and staff involved in the prehabilitation of elective patients undergoing cardiac surgery trial: a nested qualitative study, Anaesthesia, 2023 Jul 4, PMID 37402349
Akowuah E, Wagnild J, Bardgett M, Prichard J, Mathias A, Harrison S, Ogundimu E, Hancock H, Maier R, PREPs Trial investigators. A randomised controlled trial of prehabilitation in patients undergoing elective cardiac surgery, Anaesthesia, 2023 Jul 4, PMID 37402352
Bawamia B, Spray L, Wangsaputra V, Bennaceur K, Vahabi S, Stellos K, Kharatikoopaei E, Ogundimu E, Gale C, Keavney B, Maier R, Hancock H, Richardson G, Austin D, Spyridopoulos I. Activation of telomerase by TA-65 enhances immunity and reduces inflammation post myocardial infarction, GeroScience, Apr 2023, PMID: 37086366
Akowuah E, Mathias A, Bardgett M, Harrison S, Kasim A, Loughran K, Ogundimu E, Trevis J, Wagnild J, Witharana P, Hancock H, Maier R. Prehabilitation in elective patients undergoing cardiac surgery: a randomised control trial (The PrEPS Trial) – a study protocol, BMJ Open, 2023 Jan 5;13(1) PMID 36604134
2021 and 2022
Maier R, Plummer C, Kasim A, Akhter N, Ogundimu E, Maddox J, Graham J, Stewart M, Wardley A, Haney S, Vahabi S, Oxenham H, Humpfreys A, Cresti N, Verrill M, Graham R, Chang L, Hancock H, Austin D, Preventing cardiotoxicity in patients with breast cancer and lymphoma: protocol for a multicentre randomised controlled trial (PROACT), BMJ Open, 2022;12:e066252. doi: 10.1136/bmjopen-2022-066252
Gravestock P, Clark E, Morton M, Sharma S, Fisher H, Walker J, Wood R, Hancock H, Waugh N, Cooper A, Maier R, Marshall J, Chandler R, Bahl A, Crabb S, Jain S, Pedley I, Jones R, Staffurth J, Heer R. Using the AR-V7 biomarker to determine treatment in metastatic castrate resistant prostate cancer, a feasibility randomised control trial, conclusions from the VARIANT trial [version 1; peer review: 2 approved with reservations]. NIHR Open Res 2022, 2:49 https://doi.org/10.3310/nihropenres.13284.1
Frise M, Holdsworth D, Sandhu M, Mellor A, Kasim A, Hancock H, Maier R, Dorrigton K, Robbins P, Akowuah E. Non-anemic iron deficiency predicts prolonged hospitalisation following surgical aortic valve replacement: a single-centre retrospective study. J Cardiothorac Surg 17, 157 Jun 2022 https://doi.org/10.1186/s13019-022-01897-5
Wagnild J, Akowuah E, Maier R, Hancock H, Kasim A. Impact of prehabilitation on objectively measured physical activity levels in elective surgery patients: a systematic review, BMJ Open 2021;11 doi: 10.1136/bmjopen-2021-049202
Wilson N, Biggs K, Bowden S, Brown S, Dimairo M, Flight L, Hall J, Hockaday A, Jaki T, Lowe R, Murphy C, Pallmann P, Pilling M, Snowdon C, Sydes M, Villar S, Weir C, Welburn J, Yap C, Maier R, Hancock H, Wason J. Costs and staffing resource requirements for adaptive clinical trials: quantitative and qualitative results from the Costing Adaptive Trials project, BMC Medicine, Oct 2021, 19:25 PMID 34696781
Maier R, Kasim A, Zacharias J, Vale L, Graham R, Walker A, Laskawski G, Deshpande R, Goodwin A, Kendall S, Murphy G, Zamvar V, Pessotto R, Lloyd C, Dalrymple-Hay M, Casula R, Vohra H, Ciulli F, Caputo M, Stoica S, Baghai M, Niranjan G, Punjabi P, Wendler O, Marsay L, Fernandez-Garcia C, Modi P, Kirmani B, Pullan M, Muir A, Pousios D, Hancock H, Akowuah E, Minimally invasive versus conventional sternotomy for Mitral valve repair: protocol for a multicentre randomised controlled trial (UK Mini Mitral) BMJ Open 2021;11 PMID: 33853807
Hancock H, Maier R, Kasim A, Mason J, Murphy G, Goodwin A, Owens A, Akowuah E, Mini-sternotomy versus conventional sternotomy for aortic valve replacement: a randomised controlled trial, BMJ Open 2021;11:e041398. doi: 10.1136
2020 and prior
Mini-sternotomy versus conventional sternotomy for aortic valve replacement: a randomised controlled trial, Hancock HC, Maier RH, Kasim A, et al, BMJ Open, 2021;11
Does blood transfusion have an effect on outcomes after aortic valve replacement surgery? Bayliss CD, Maier RH, Kasim A, Hancock H, Akowuah E Heart, Lung and Circulation, 2020, 30(6)
Ensuring that COVID-19 Research is Inclusive – guidance from the NIHR INCLUDE project, Witham MD, Anderson E, Carroll C, Dark PM, Down K, Hall AS, Knee J, Maher ER, Maier RH, Mountain GA, Nestor G, Oliva L, Wason J, Rochester L, BMJ Open, 2020;10
Developing a roadmap to improve trial delivery for under-served groups: results from a UK multi-stakeholder process, Witham MD, Anderson E, Carroll C, Dark PM, Down K, Hall AS, Knee J, Maier RH, Mountain GA, Nestor G, Oliva L, Prowse SR, Tortice A, Wason J, Rochester L, Trials, 2020 (21)694
Telomerase activation to reverse immunosenescence in elderly patients with acute coronary syndrome: Protocol for a randomised pilot trial, Maier R, Bawamia B, Bennaceur K, Dunn S, Marsay L, Amoah R, Kasim A, Filby A, Austin D, Hancock H, Spyridopoulos I, JMIR Res Protoc, 2020 23;9(9)
Prostate cancer androgen receptor splice variant 7 biomarker study – A multicentre randomised feasibility trial of biomarker-guided personalised treatment in patients with advanced prostate cancer (the VARIANT trial) study protocol. Clark E, Morton M, Sharma S, Fisher H, Howel D, Walker J, Wood R, Hancock H, Maier R, Marshall J, Bahl A, Crabb S, Jain S, Pedley I, Jones R, Staffurth J, Heer R. BMJ Open 2019, 9(12), e034708.
A randomized double-blinded sham-controlled cross-over trial of tined-lead sacral nerve stimulation testing for chronic constipation.Yiannakou Y, Etherson K, Close H, Kasim A, Mercer-Jones M, Plusa S, Maier R, Green S, Cundall J, Knowles C, Mason J. European journal of gastroenterology & hepatology 2019, 31(6), 653-660.
Manubrium-limited ministernotomy versus conventional sternotomy for aortic valve replacement (MAVRIC): Study protocol for a randomised controlled trial.Akowuah E, Goodwin AT, Owens WA, Hancock HC, Maier R, Kasim A, Mellor A, Khan K, Murphy G, Mason J. Trials, 2017, 18(1), 46.
Manubrium-limited ministernotomy versus conventional sternotomy for aortic valve replacement: A randomised controlled trial (MAVRIC), Akowuah E, Goodwin AT, Owens WA, Hancock HC, Maier R, Kasim A, Mellor A, Khan K, Murphy G, Mason J, Society for Cardiothoracic Surgery Annual Meeting & Cardiothoracic Forum, 2017, Belfast, Ireland, SCTS
Multidetector CT improving surgical outcomes in breast cancer (MISO-BC): A randomised controlled trial, Cox J, Hancock H, Maier R, Spratt J, Lee CM, Bhatti A, Mason J, Breast, 2017, 32, p.217-224.
Tined lead test stimulation to predict long-term benefit from sacral nerve stimulation in patients with chronic constipation (TiLTS-cc trial), Yiannakou Y, Etherson K, Close H, Kasim A, Mercer-Jones M, Plusa S, Maier R, Green S, Cundall J, Knowles C, Mason J, European Society of Coloproctology 11th Scientific and Annual Meeting, 2016, Milan, Italy.
Narrow band imaging optical diagnosis of small colorectal polyps in routine clinical practice: The Detect Inspect Characterise Resect and Discard 2 (DISCARD 2) study, Rees CJ, Rajasekhar PT, Wilson A, Close H, Rutter MD, Saunders BP, East JE, Maier R, Moorghen M, Muhammad U, Hancock H, Jayaprakash A, MacDonald C, Ramadas A, Dhar A, Mason JM, Gut, 2016, 66(5), p.887-895.
Minimally invasive thoracoscopically-guided right minithoracotomy versus conventional sternotomy for mitral valve repair: a multicentre randomised controlled trial (UK Mini Mitral), Akowuah E, Hancock H, Maier R, Kasim A, Zacharias J, Deshpande R, Birdi I, Vale L, Livesey S, Stewart M, Murphy G, NIHR Research Project, 2016.
Biodegradable stent or balloon dilatation for benign oesophageal stricture: Pilot randomised controlled trial, Dhar A, Close H, Hancock H, Maier R, Wilson D, Mason JM, Vishwanath YKS, Rees C, Dwarakanath D, World Journal of Gastroenterology, 2014, 20(48), p.18199-18206.