Background
Bicarbonate concentration is measured as part of the electrolyte profile on the Advia analysers. The results obtained are not identical to those from a blood gas analyser since they include dissolved CO2, carbonic acid and carbamine compounds, but differ by approximately 3 mmol/L. Measurement of bicarbonate is of clinical use as a measure of acid-base balance in the bloodstream.
Reference ranges
22 – 29 mmol/l
Associated diseases
Higher than normal levels:
- Hyperaldosteronism
- Cushing syndrome
Lower than normal levels:
- Ketoacidosis
- Lactic acidosis
- Kidney disease
- Addison disease
Specimen requirements
Sample type:
- Serum or Lithium Heparin Plasma.
Sample identification:
- Three patient identifiers from:
- Name
- D.O.B.
- Address
- N.H.S. number
- Unit Number should match on the specimen and request form. This check may be performed prior to centrifugation by the Central Sort department.
Turnaround time
2 hours