Description
Present in patients with either isolated primary testicular failure or associated with other autoimmune endocrinopathies e.g. Hypoadrenalism, Insulin dependent diabetes, Pernicious anaemia (autoimmune polyglandular syndromes). The autoantibodies are closely related to antibodies to adrenal cortex and ovary with which they can also be found. All recognise different forms of cytochrome p450. Testicular form forms are P450c17 and P450 scc.
Indication
Testicular failure
Sample
Serum Separator Tube (SST)
Assay details
Indirect immunofluorescence primate tissue
Restrictions
Referred Test
Reference range
Negative/positive
Turnaround time
28 days
Analysing laboratory
Sheffield PRU